Cholesterol Side-Chain Cleavage Enzyme
"Cholesterol Side-Chain Cleavage Enzyme" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mitochondrial cytochrome P450 enzyme that catalyzes the side-chain cleavage of C27 cholesterol to C21 pregnenolone in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11A1 gene, catalyzes the breakage between C20 and C22 which is the initial and rate-limiting step in the biosynthesis of various gonadal and adrenal steroid hormones.
| Descriptor ID |
D002786
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| MeSH Number(s) |
D08.244.453.484.250 D08.244.453.915.212 D08.811.682.690.708.170.425.250 D08.811.682.690.708.170.915.212 D12.776.422.220.453.484.250 D12.776.422.220.453.915.212
|
| Concept/Terms |
Cholesterol Side-Chain Cleavage Enzyme- Cholesterol Side-Chain Cleavage Enzyme
- Cholesterol Side Chain Cleavage Enzyme
- Cholesterol Desmolase
- Cytochrome P-450(scc)
- CYP11A1
- CYP 11A1
- Cytochrome P450 11A1
- Cytochrome P-450 CYP11A1
- Cytochrome P 450 CYP11A1
- Cholesterol Monooxygenase (Side-Chain-Cleaving)
- 20,22-Desmolase
- 20,22 Desmolase
- Cytochrome P450scc
|
Below are MeSH descriptors whose meaning is more general than "Cholesterol Side-Chain Cleavage Enzyme".
Below are MeSH descriptors whose meaning is more specific than "Cholesterol Side-Chain Cleavage Enzyme".
This graph shows the total number of publications written about "Cholesterol Side-Chain Cleavage Enzyme" by people in this website by year, and whether "Cholesterol Side-Chain Cleavage Enzyme" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cholesterol Side-Chain Cleavage Enzyme" by people in Profiles.
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Polymorphisms in steroid hormone biosynthesis genes and risk of breast cancer and fibrocystic breast conditions in Chinese women. Cancer Epidemiol Biomarkers Prev. 2008 May; 17(5):1066-73.