Kris F. Wain, PhD, is an Investigator and Health Economist at the Institute for Health Research. Dr. Wain’s research focuses on health outcomes and healthcare costs across the cancer care continuum. He also evaluates and implements innovative healthcare models aimed at improving access to care, increasing use of high-value and preventive services, and improving health outcomes. Dr. Wain earned his Master of Science degree in Health Economics from the University of Colorado Denver and completed his doctoral training in Health Economics at the Colorado School of Public Health . He is the principal investigator of a National Cancer Institute (NCI) funded study examining barriers to lung cancer screening and recently led an intervention to “nudge” patients toward cancer screening that has been incorporated into standard care at Kaiser Permanente Colorado. He has also worked extensively with the NCI-funded Lung PROSPR Research Center (Lung-PRC) to improve lung cancer screening.
Director, Kaiser Permanente Vaccine Study Center
Associate Director, Cardiovascular, Kidney, and Metabolic Health
Medical Director, Delivery Science and Applied Research, The Permanente Medical Group,
Wain K, Maiyani M, Carroll NM, Meza R, Greenlee RT, Neslund-Dudas C, Odelberg MR, Oshiro C, Ritzwoller DP
Patterns of Medical Care Cost by Service Type Associated With Lung Cancer Screening. Med Care. 2025 Jun 02.
Patterns of Medical Care Cost by Service Type Associated With Lung Cancer Screening.
Hambidge SJ, Ross C, Shoup JA, Wain K, Narwaney K, Breslin K, Weintraub ES, McNeil MM
Integration of data from a safety net health care system into the Vaccine Safety Datalink. Vaccine. 2017 03 01; 35(9):1329-1334.
Integration of data from a safety net health care system into the Vaccine Safety Datalink.
Narwaney KJ, Breslin K, Ross CA, Shoup JA, Wain KF, Weintraub ES, McNeil MM, Hambidge SJ
Vaccine adverse events in a safety net healthcare system and a managed care organization. Vaccine. 2017 03 01; 35(9):1335-1340.
Vaccine adverse events in a safety net healthcare system and a managed care organization.
Maiyani M, Wain K, Carroll NM, Eisenstein J, Hixon B, Greenlee RT, Neslund-Dudas C, Oshiro C, Ritzwoller DP
Impact of COVID-19 on Timeliness of Receiving Systemic Therapy for Patients Diagnosed with Lung Cancer. J Cancer Res Pract. 2025 Jul-Sep; 12(3):76-84.
Impact of COVID-19 on Timeliness of Receiving Systemic Therapy for Patients Diagnosed with Lung Cancer.
Burnett-Hartman AN, Carroll NM, Wain KF, Hixon BP, Vachani A, Greenlee RT, Honda SA, Kim RY, Neslund-Dudas C, Oshiro CES, Rendle KA, Simoff M, Ritzwoller DP
Lung Cancer Yield by Baseline Screening Lung CT Screening Reporting and Data System (Lung-RADS) Assignment and Patient Factors: The Population-Based Research to Optimize the Screening Process Lung Consortium. CHEST Pulm. 2026 Jun; 4(2).
Lung Cancer Yield by Baseline Screening Lung CT Screening Reporting and Data System (Lung-RADS) Assignment and Patient Factors: The Population-Based Research to Optimize the Screening Process Lung Consortium.
Hoppman-Chaney N, Wain K, Seger PR, Superneau DW, Hodge JC
Identification of single gene deletions at 15q13.3: further evidence that CHRNA7 causes the 15q13.3 microdeletion syndrome phenotype. Clin Genet. 2013 Apr; 83(4):345-51.
Identification of single gene deletions at 15q13.3: further evidence that CHRNA7 causes the 15q13.3 microdeletion syndrome phenotype.
Wain KF, Steiner CA, Daddato AE, McQuillan DB, Litten JD, Jentz C, Jessen AR, Gozansky WS
Journal of the American Geriatrics Society
Evaluating the Association of a Self-Guided, Asynchronous, Balance Exercise Application on Fall-Related Injuries. J Am Geriatr Soc. 2026 Aug; 74(8):2255-2264.
Evaluating the Association of a Self-Guided, Asynchronous, Balance Exercise Application on Fall-Related Injuries.
Ritzwoller DP, Carroll NM, Wain KF, Hixon BP, Kim RY, Maiyani M, Steiner JS
Examining trends in lung cancer screening over 10?years: Eligibility, participation, cancer detection, and quality implications. Cancer. 2025 Dec 15; 131(24):e70211.
Examining trends in lung cancer screening over 10?years: Eligibility, participation, cancer detection, and quality implications.
Wain KF, Daddato AE, Dollar B, Lagrotteria J, Young HM, Satake A, Zeng C, Boxer RS
Caregivers with poorer health are less likely to engage in an intervention to prepare for their own health care emergency. Gerontologist. 2026 06 09; 66(7).
Caregivers with poorer health are less likely to engage in an intervention to prepare for their own health care emergency.
Executive Director, Institute for Health Research
Assistant Investigator / Research Scientist I
Senior Investigator / Research Scientist III
Wagner NM, Binswanger IA, Shetterly SM, Rinehart DJ, Wain KF, Hopfer C, Glanz JM
Development and validation of a prediction model for opioid use disorder among youth. Drug Alcohol Depend. 2021 Aug 28; 227:108980.
Development and validation of a prediction model for opioid use disorder among youth.
Center for Integrated Health Care Research
Groom HC, Crane B, Naleway AL, Weintraub E, Daley MF, Wain K, Beth Kurilo M, Burganowski R, DeSilva MB, Donahue JG, Glenn SC, Goddard K, Jackson ML, Kharbanda EO, Lewis N, Lou Y, Lugg M, Scotty E, Sy LS, Williams JTB, Irving SA
Monitoring vaccine safety using the vaccine safety Datalink: Assessing capacity to integrate data from Immunization Information systems. Vaccine. 2022 01 31; 40(5):752-756.
Monitoring vaccine safety using the vaccine safety Datalink: Assessing capacity to integrate data from Immunization Information systems.
Kaiser Permanente Bernard J. Tyson School of Medicine
Wain K, Carroll NM, Honda S, Oshiro C, Ritzwoller DP
Individuals Eligible for Lung Cancer Screening Less Likely to Receive Screening When Enrolled in Health Plans With Deductibles. Med Care. 2023 Oct 01; 61(10):665-673.
Individuals Eligible for Lung Cancer Screening Less Likely to Receive Screening When Enrolled in Health Plans With Deductibles.
Lewandowski RE, O'Connor B, Bertagnolli A, Beck A, Tinoco A, Gardner WP, Jelinek-Berents CX, Newton DA, Wain KF, Boggs JM, Brace NE, deSa P, Scholle SH, Hoagwood K, Horwitz SM
Screening for and Diagnosis of Depression Among Adolescents in a Large Health Maintenance Organization. Psychiatr Serv. 2016 06 01; 67(6):636-41.
Screening for and Diagnosis of Depression Among Adolescents in a Large Health Maintenance Organization.
Glanz JM, Mueller SR, Narwaney KJ, Wagner N, Xu S, Kraus C, Wain K, Botts S, Binswanger IA
Effectiveness of direct patient outreach with a narrative naloxone and overdose prevention video to patients prescribed long-term opioid therapy in the USA: the Naloxone Navigator randomised clinical trial. BMJ Public Health. 2024 Jul; 2(1).
Effectiveness of direct patient outreach with a narrative naloxone and overdose prevention video to patients prescribed long-term opioid therapy in the USA: the Naloxone Navigator randomised clinical trial.
Carroll NM, Eisenstein J, Wain KF, Freml JM, Greenlee RT, Honda SA, Neslund-Dudas C, Rendle KA, Vachani A, Ritzwoller DP
Patterns of recurrence among adults diagnosed with screen-detected lung cancer. Cancer Epidemiol. 2025 Apr; 95:102777.
Patterns of recurrence among adults diagnosed with screen-detected lung cancer.
Temporal Association Between Maternal Depression and Paternal Postpartum Depression. Am J Prev Med. 2025 Mar 04.
Temporal Association Between Maternal Depression and Paternal Postpartum Depression.