Granulomatous Disease, Chronic

"Granulomatous Disease, Chronic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation. When chronic granulomatous disease is caused by mutations in the CYBB gene, the condition is inherited in an X-linked recessive pattern. When chronic granulomatous disease is caused by CYBA, NCF1, NCF2, or NCF4 gene mutations, the condition is inherited in an autosomal recessive pattern.

Descriptor ID	D006105
MeSH Number(s)	C15.378.553.774.535 C16.320.322.233 C20.673.774.535
Concept/Terms	Granulomatous Disease, Chronic Granulomatous Disease, Chronic Chronic Granulomatous Diseases Granulomatous Diseases, Chronic Chronic Granulomatous Disease Autosomal Recessive Chronic Granulomatous Disease Autosomal Recessive Chronic Granulomatous Disease Granulomatous Disease, Chronic, X-Linked Granulomatous Disease, Chronic, X-Linked Cytochrome B-Negative Granulomatous Disease, Chronic, X-Linked X-Linked Chronic Granulomatous Disease X Linked Chronic Granulomatous Disease Granulomatous Disease, Chronic, X-Linked, Variant Chronic Granulomatous Disease, Atypical Chronic Granulomatous Disease, X-Linked Chronic Granulomatous Disease, X Linked Cytochrome B-Positive Granulomatous Disease, Chronic, X-Linked

Below are MeSH descriptors whose meaning is more general than "Granulomatous Disease, Chronic".

Diseases [C]
Hemic and Lymphatic Diseases [C15]
Hematologic Diseases [C15.378]
Leukocyte Disorders [C15.378.553]
Phagocyte Bactericidal Dysfunction [C15.378.553.774]
Granulomatous Disease, Chronic [C15.378.553.774.535]
Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
Genetic Diseases, Inborn [C16.320]
Genetic Diseases, X-Linked [C16.320.322]
Granulomatous Disease, Chronic [C16.320.322.233]
Immune System Diseases [C20]
Immunologic Deficiency Syndromes [C20.673]
Phagocyte Bactericidal Dysfunction [C20.673.774]
Granulomatous Disease, Chronic [C20.673.774.535]

Below are MeSH descriptors whose meaning is related to "Granulomatous Disease, Chronic".

Below are MeSH descriptors whose meaning is more specific than "Granulomatous Disease, Chronic".

publications

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