Angiopoietin-like 4 Protein
"Angiopoietin-like 4 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A secreted angiopoietin-like protein expressed under hypoxic conditions by ENDOTHELIAL CELLS. It inhibits cell proliferation, cell migration, and tubule formation; the inactive form accumulates in the endothelial EXTRACELLULAR MATRIX, reducing vascular leakage. ANGPTL4 has direct roles in regulating glucose and lipid metabolism, as well as INSULIN SENSITIVITY, and may also function as a regulator of angiogenesis and tumorigenesis.
| Descriptor ID |
D000075803
|
| MeSH Number(s) |
D12.644.276.100.050.500 D12.776.467.100.050.500 D23.529.100.050.500
|
| Concept/Terms |
Angiopoietin-like 4 Protein- Angiopoietin-like 4 Protein
- Angiopoietin like 4 Protein
- ANGPTL4 Protein
- Angiopoietin-related Protein 4
- Angiopoietin related Protein 4
- Angiopoietin-like Protein 4
- Angiopoietin like Protein 4
|
Below are MeSH descriptors whose meaning is more general than "Angiopoietin-like 4 Protein".
Below are MeSH descriptors whose meaning is more specific than "Angiopoietin-like 4 Protein".
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Below are the most recent publications written about "Angiopoietin-like 4 Protein" by people in Profiles.
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Angiopoietin-like 4 (ANGPTL4) gene polymorphisms and risk of brain arteriovenous malformations. Cerebrovasc Dis. 2011; 31(4):338-45.