"Prion Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Membrane glycosylphosphatidylinositol-anchored glycoproteins that may aggregate into rod-like structures. The prion protein (PRNP) gene is characterized by five TANDEM REPEAT SEQUENCES that encode a highly unstable protein region of five octapeptide repeats. Mutations in the repeat region and elsewhere in this gene are associated with CREUTZFELDT-JAKOB DISEASE; FATAL FAMILIAL INSOMNIA; GERSTMANN-STRAUSSLER DISEASE; Huntington disease-like 1, and KURU.
Descriptor ID |
D000072002
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MeSH Number(s) |
D12.776.395.550.448.600 D12.776.543.484.500.625 D12.776.543.550.418.600 D12.776.785.340
|
Concept/Terms |
Prion Proteins- Prion Proteins
- Prion Protein
- CD230 Antigen
- Antigen, CD230
- PrP Proteins
- Fatal Familial Insomnia Protein
- Major Prion Protein
- Prion Protein, Major
- Creutzfeldt-Jakob Disease Protein
- Creutzfeldt Jakob Disease Protein
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Below are MeSH descriptors whose meaning is more general than "Prion Proteins".
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