"Soluble Guanylyl Cyclase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mammalian enzyme composed of a heterodimer of alpha and beta subunits. Each subunit consists of four domains; N-terminal HNOX domain, PAS-like domain, a coiled-coil domain, and a C-terminal catalytic domain. All four domains are homologous proteins with a similar conformation of functional domains. Soluble guanylate cyclase catalyzes the formation of cyclic GMP from GTP, and is a key enzyme of the nitric oxide signaling pathway involved in the regulation of a variety of biological and physiological processes in mammals.
| Descriptor ID |
D000071756
|
| MeSH Number(s) |
D08.811.520.650.600.750 D12.644.360.350.500 D12.776.476.350.500
|
| Concept/Terms |
Soluble Guanylyl Cyclase- Soluble Guanylyl Cyclase
- Cyclase, Soluble Guanylyl
- Guanylyl Cyclase, Soluble
- Soluble Guanylate Cyclase
- Cyclase, Soluble Guanylate
- Guanylate Cyclase, Soluble
- Nitric Oxide-Sensitive Guanylyl Cyclase
- Nitric Oxide Sensitive Guanylyl Cyclase
- Receptor, Nitric Oxide
- Nitric Oxide Receptor
- Oxide Receptor, Nitric
- Nitric Oxide Receptors
- Oxide Receptors, Nitric
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Below are MeSH descriptors whose meaning is more general than "Soluble Guanylyl Cyclase".
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Below are the most recent publications written about "Soluble Guanylyl Cyclase" by people in Profiles.