"Axin Signaling Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A specific complex of WNT SIGNALING PATHWAY proteins that mediates the phosphorylation-dependent destruction of cytosolic BETA-CATENIN. The complex is disrupted by cell surface binding of WNT PROTEINS, which allows beta-catenin levels to rise to the point where they migrate to the CELL NUCLEUS and activate transcription.
| Descriptor ID |
D060465
|
| MeSH Number(s) |
D05.500.117 D12.776.476.081
|
| Concept/Terms |
Axin Signaling Complex- Axin Signaling Complex
- Signaling Complex, Axin
- Axin Signaling Complex Proteins
- beta-Catenin Destruction Complex
- Destruction Complex, beta-Catenin
- beta Catenin Destruction Complex
|
Below are MeSH descriptors whose meaning is more general than "Axin Signaling Complex".
Below are MeSH descriptors whose meaning is more specific than "Axin Signaling Complex".
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