"Pyroglobulins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Atypical gamma immunoglobulins characterized by their irreversible heat denaturation at 56-degrees C. Pyroprecipitation is inhibited at pH below 3 and above 9. The presence of pyroglobulins in the serum is the cause of pyroglobulinemia. They are frequently present in multiple myeloma and the pyroglobulin precipitate binds complement, reacts with rheumatoid factor, produces passive cutaneous anaphylaxis, generalized passive anaphylaxis and passive Arthus-type phenomena.
| Descriptor ID |
D011750
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| MeSH Number(s) |
D12.776.124.486.485.900.700 D12.776.124.790.651.900.700 D12.776.377.715.548.900.700
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pyroglobulins".
Below are MeSH descriptors whose meaning is more specific than "Pyroglobulins".
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Below are the most recent publications written about "Pyroglobulins" by people in Profiles.