"Cytochrome P-450 CYP1A1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A liver microsomal cytochrome P-450 monooxygenase capable of biotransforming xenobiotics such as polycyclic hydrocarbons and halogenated aromatic hydrocarbons into carcinogenic or mutagenic compounds. They have been found in mammals and fish. This enzyme, encoded by CYP1A1 gene, can be measured by using ethoxyresorufin as a substrate for the ethoxyresorufin O-deethylase activity.
| Descriptor ID |
D019363
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| MeSH Number(s) |
D08.244.453.005.332 D08.244.453.100.500 D08.811.682.690.708.170.010.277 D08.811.682.690.708.170.020.500 D12.776.422.220.453.010.332 D12.776.422.220.453.100.500
|
| Concept/Terms |
Cytochrome P-450 CYP1A1- Cytochrome P-450 CYP1A1
- Cytochrome P 450 CYP1A1
- EROD
- Ethoxyresorufin Dealkylase
- Ethylresorufin O-Deethylase
- CYP1A1 Protein
- 7-Ethoxyresorufin O-Deethylase
- CYP1A1
- Cytochrome P450 IA1
- Ethoxyresorufin O-Deethylase
- CYP 1A1
|
Below are MeSH descriptors whose meaning is more general than "Cytochrome P-450 CYP1A1".
Below are MeSH descriptors whose meaning is more specific than "Cytochrome P-450 CYP1A1".
This graph shows the total number of publications written about "Cytochrome P-450 CYP1A1" by people in this website by year, and whether "Cytochrome P-450 CYP1A1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 2 | 1 | 3 |
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Below are the most recent publications written about "Cytochrome P-450 CYP1A1" by people in Profiles.
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Sex steroid metabolism polymorphisms and mammographic density in pre- and early perimenopausal women. Breast Cancer Res. 2009; 11(4):R51.
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CYP1A1/2 haplotypes and lung cancer and assessment of confounding by population stratification. Cancer Res. 2009 Mar 15; 69(6):2340-8.
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Variants in hormone-related genes and the risk of biliary tract cancers and stones: a population-based study in China. Carcinogenesis. 2009 Apr; 30(4):606-14.
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Genetic variation in hormone metabolizing genes and risk of testicular germ cell tumors. Cancer Causes Control. 2008 Nov; 19(9):917-29.
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CYP1A1 and CYP1B1 genotypes, haplotypes, and TCDD-induced gene expression in subjects from Seveso, Italy. Toxicology. 2005 Feb 14; 207(2):191-202.
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The CYP1A1 genotype may alter the association of meat consumption patterns and preparation with the risk of colorectal cancer in men and women. J Nutr. 2005 Feb; 135(2):179-86.
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CYP1A1, cigarette smoking, and colon and rectal cancer. Am J Epidemiol. 2004 Nov 01; 160(9):842-52.