Header Logo

Helix-Turn-Helix Motifs

"Helix-Turn-Helix Motifs" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

expand / collapse MeSH information
The first DNA-binding protein motif to be recognized. Helix-turn-helix motifs were originally identified in bacterial proteins but have since been found in hundreds of DNA-BINDING PROTEINS from both eukaryotes and prokaryotes. They are constructed from two alpha helices connected by a short extended chain of amino acids, which constitute the "turn." The two helices are held at a fixed angle, primarily through interactions between the two helices. (From Alberts et al., Molecular Biology of the Cell, 3d ed, p408-9)


expand / collapse publications
This graph shows the total number of publications written about "Helix-Turn-Helix Motifs" by people in this website by year, and whether "Helix-Turn-Helix Motifs" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.

© 2024 Kaiser Permanente