"Sp1 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Promoter-specific RNA polymerase II transcription factor that binds to the GC box, one of the upstream promoter elements, in mammalian cells. The binding of Sp1 is necessary for the initiation of transcription in the promoters of a variety of cellular and viral GENES.
| Descriptor ID |
D016329
|
| MeSH Number(s) |
D12.776.260.522.750.249 D12.776.930.375.750.249
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Sp1 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "Sp1 Transcription Factor".
This graph shows the total number of publications written about "Sp1 Transcription Factor" by people in this website by year, and whether "Sp1 Transcription Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sp1 Transcription Factor" by people in Profiles.
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Genetic variants in transcription factors are associated with the pharmacokinetics and pharmacodynamics of metformin. Clin Pharmacol Ther. 2014 Sep; 96(3):370-9.