"Genes, erbB-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				The proto-oncogene c-erbB-1 codes for the epidermal growth factor receptor. Its name originates from the viral homolog v-erbB which was isolated from an avian erythroblastosis virus (AEV) where it was contained as a fragment of the chicken c-ErbB-1 gene lacking the amino-terminal ligand-binding domain. Overexpression of erbB-1 genes occurs in a wide range of tumors, commonly squamous carcinomas of various sites and less commonly adenocarcinomas. The human c-erbB-1 gene is located in the chromosomal region 7p14 and 7p12.
    
			
			
				
				
					
						| Descriptor ID | D018773 | 
					
						| MeSH Number(s) | G05.360.340.024.340.375.500.791.295.300 | 
					
						| Concept/Terms | Genes, erbB-1Genes, erbB-1Genes, erbB1Gene, erbB1erbB1 GeneerbB1 GeneserbB-1 GeneserbB 1 GeneserbB-1 Gene
 v-erbB Genesv-erbB Genesv erbB Genesv-erbB Genev-erbB Oncogenesv erbB Oncogenesv-erbB Oncogene
 c-erbB-1 Genesc-erbB-1 Genesc erbB 1 Genesc-erbB-1 GeneEGFR GenesEpidermal Growth Factor Receptor Genesc-erbB-1 Proto-Oncogenesc erbB 1 Proto Oncogenesc-erbB-1 Proto-OncogeneGenes, EGFREGFR Gene
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				Below are MeSH descriptors whose meaning is more general than "Genes, erbB-1".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "Genes, erbB-1".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
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