CD4-Positive T-Lymphocytes
                             
                            
                            
                                
                            
                            
                                
                            
                            
                            
                                
                                    
                                            
	"CD4-Positive T-Lymphocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				A critical subpopulation of T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the T4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes.
    
			
			
				
				
					
						| Descriptor ID | 
										
							D015496
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						| MeSH Number(s) | 
						
							 A11.118.637.555.567.569.200 A15.145.229.637.555.567.569.200 A15.382.490.555.567.569.200 
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						| Concept/Terms | 
						
							CD4-Positive T-Lymphocytes- CD4-Positive T-Lymphocytes
 - CD4 Positive T Lymphocytes
 - CD4-Positive T-Lymphocyte
 - T-Lymphocyte, CD4-Positive
 - T-Lymphocytes, CD4-Positive
 - CD4-Positive Lymphocytes
 - CD4-Positive Lymphocyte
 - Lymphocyte, CD4-Positive
 - Lymphocytes, CD4-Positive
 - T4 Cells
 - T4 Cell
 - T4 Lymphocytes
 - T4 Lymphocyte
 
  
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				Below are MeSH descriptors whose meaning is more general than "CD4-Positive T-Lymphocytes".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "CD4-Positive T-Lymphocytes".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "CD4-Positive T-Lymphocytes" by people in this website by year, and whether "CD4-Positive T-Lymphocytes" was a major or minor topic of these publications. 
				
					
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		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 2002 | 1 | 0 | 1 | 
| 2006 | 1 | 0 | 1 | 
| 2010 | 0 | 1 | 1 | 
| 2011 | 0 | 1 | 1 | 
| 2012 | 1 | 0 | 1 | 
| 2015 | 1 | 1 | 2 | 
| 2017 | 1 | 1 | 2 | 
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				Below are the most recent publications written about "CD4-Positive T-Lymphocytes" by people in Profiles.
						
					
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Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes. Nat Genet. 2021 07; 53(7):962-971.
															
								 
							
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Immunogenicity and Safety of the HZ/su Adjuvanted Herpes Zoster Subunit Vaccine in Adults Previously Vaccinated With a Live Attenuated Herpes Zoster Vaccine. J Infect Dis. 2017 12 12; 216(11):1343-1351.
															
								 
							
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Association of CD4+ T-cell Count, HIV-1 RNA Viral Load, and Antiretroviral Therapy With Kaposi Sarcoma Risk Among HIV-infected Persons in the United States and Canada. J Acquir Immune Defic Syndr. 2017 08 01; 75(4):382-390.
															
								 
							
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Stromal immune infiltration in HIV-related diffuse large B-cell lymphoma is associated with HIV disease history and patient survival. AIDS. 2015 Sep 24; 29(15):1943-51.
															
								 
							
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Body mass index and early CD4 T-cell recovery among adults initiating antiretroviral therapy in North America, 1998-2010. HIV Med. 2015 Oct; 16(9):572-7.
															
								 
							
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Upregulated baseline plasma CCL19 and CCR7 cell-surface expression on monocytes in early rheumatoid arthritis normalized during treatment and CCL19 correlated with radiographic progression. Scand J Rheumatol. 2014; 43(2):91-100.
															
								 
							
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CCR5 expression is elevated on endocervical CD4+ T cells in healthy postmenopausal women. J Acquir Immune Defic Syndr. 2012 Mar 01; 59(3):221-8.
															
								 
							
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Reappraisal of the provisional entity primary cutaneous CD4+ small/medium pleomorphic T-cell lymphoma: a series of 10 adult and pediatric patients and review of the literature. J Am Acad Dermatol. 2011 Oct; 65(4):739-748.
															
								 
							
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Interferon-gamma-producing T cells, pregnancy, and postpartum relapses of multiple sclerosis. Arch Neurol. 2010 Jan; 67(1):51-7.
															
								 
							
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Variability and gender differences in memory T cell immunity to varicella-zoster virus in healthy adults. Vaccine. 2006 Aug 14; 24(33-34):5913-8.