Header Logo

ATP Binding Cassette Transporter, Sub-Family B

"ATP Binding Cassette Transporter, Sub-Family B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

expand / collapse MeSH information
A subfamily of transmembrane proteins from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS that are closely related in sequence to ATP-BINDING CASSETTE, SUB-FAMILY B, MEMBER 1. When overexpressed, they function as ATP-dependent efflux pumps able to extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing multidrug resistance (DRUG RESISTANCE, MULTIPLE). Although ATP BINDING CASSETTE TRANSPORTER, SUB-FAMILY B share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.


expand / collapse publications
This graph shows the total number of publications written about "ATP Binding Cassette Transporter, Sub-Family B" by people in this website by year, and whether "ATP Binding Cassette Transporter, Sub-Family B" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.

© 2024 Kaiser Permanente