"RNA Caps" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nucleic acid structures found on the 5' end of eukaryotic cellular and viral messenger RNA and some heterogeneous nuclear RNAs. These structures, which are positively charged, protect the above specified RNAs at their termini against attack by phosphatases and other nucleases and promote mRNA function at the level of initiation of translation. Analogs of the RNA caps (RNA CAP ANALOGS), which lack the positive charge, inhibit the initiation of protein synthesis.
Descriptor ID |
D012315
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MeSH Number(s) |
D03.633.100.759.646.454.700 D13.444.735.544.500 D13.695.667.454.700 D13.695.827.426.700
|
Concept/Terms |
RNA Caps- RNA Caps
- Caps, RNA
- 5' Capped RNA
- RNA, 5' Capped
- 5' mRNA Cap Structure
|
Below are MeSH descriptors whose meaning is more general than "RNA Caps".
Below are MeSH descriptors whose meaning is more specific than "RNA Caps".
This graph shows the total number of publications written about "RNA Caps" by people in this website by year, and whether "RNA Caps" was a major or minor topic of these publications.
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Below are the most recent publications written about "RNA Caps" by people in Profiles.
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Terminal 7-methyl-guanosine cap structure on the normally uncapped 5' noncoding region of poliovirus mRNA inhibits its translation in mammalian cells. J Virol. 1991 Nov; 65(11):6312-5.