A motor neuron disease marked by progressive weakness of the muscles innervated by cranial nerves of the lower brain stem. Clinical manifestations include dysarthria, dysphagia, facial weakness, tongue weakness, and fasciculations of the tongue and facial muscles. The adult form of the disease is marked initially by bulbar weakness which progresses to involve motor neurons throughout the neuroaxis. Eventually this condition may become indistinguishable from AMYOTROPHIC LATERAL SCLEROSIS. Fazio-Londe syndrome is an inherited form of this illness which occurs in children and young adults. (Adams et al., Principles of Neurology, 6th ed, p1091; Brain 1992 Dec;115(Pt 6):1889-1900)

Descriptor ID	D010244
MeSH Number(s)	C10.574.562.300 C10.668.467.300
Concept/Terms	Bulbar Palsy, Progressive Bulbar Palsy, Progressive Bulbar Palsies, Progressive Palsies, Progressive Bulbar Palsy, Progressive Bulbar Progressive Bulbar Palsies Progressive Bulbar Palsy Bulbar Palsy Bulbar Palsy Bulbar Palsies Palsies, Bulbar Palsy, Bulbar Paralysis, Bulbar Bulbar Paralyses Bulbar Paralysis Childhood Progressive Bulbar Palsy Childhood Progressive Bulbar Palsy Bulbar Palsy, Progressive, Of Childhood Progressive Bulbar Palsy of Childhood Fazio-Londe Syndrome Fazio-Londe Syndrome Fazio Londe Syndrome Fazio-Londe Disease Fazio Londe Disease

Below are MeSH descriptors whose meaning is more general than "Bulbar Palsy, Progressive".

Below are MeSH descriptors whose meaning is related to "Bulbar Palsy, Progressive".

Below are MeSH descriptors whose meaning is more specific than "Bulbar Palsy, Progressive".